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1

Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2

Zak, Krzysztof M., Grudnik, Przemyslaw, Magiera, Katarzyna, Dömling, Alexander, Dubin, Grzegorz, Holak, Tad A.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.93 MB

english, 2017

2

Crystal structure of ADP-dependent glucokinase from Methanocaldococcus jannaschii in complex with 5-iodotubercidin reveals phosphoryl transfer mechanism

Tokarz, Piotr, Wiśniewska, Magdalena, Kamiński, Marcin M., Dubin, Grzegorz, Grudnik, Przemysław

Journal:

Protein Science

Year:

2018

Language:

english

File:

PDF, 1.09 MB

english, 2018

3

Protein targeting by the signal recognition particle

Grudnik, Przemyslaw, Bange, Gert, Sinning, Irmgard

Journal:

Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 226 KB

english, 2009

4

Risk assessment in fish welfare, applications and limitations

Christine Müller-Graf, Franck Berthe, Tomasz Grudnik, Ed Peeler, Ana Afonso

Journal:

Fish Physiology and Biochemistry

Year:

2012

Language:

english

File:

PDF, 238 KB

english, 2012

5

Myriophyllum spicatum and Najas marina as Bioindicators of Trace Element Contamination in Lakes

Grudnik, Zdenka Mazej, Germ, Mateja

Journal:

Journal of Freshwater Ecology

Year:

2010

Language:

english

File:

PDF, 565 KB

english, 2010

6

Reducing the noise emitted from a domestic clothes-drying machine

Holecek, Nikola, Sirok, Brane, Hocevar, Marko, Podgornik, Rudolf, Grudnik, Rok

Journal:

Noise Control Engineering Journal

Year:

2006

Language:

english

File:

PDF, 994 KB

english, 2006

7

Spatial pattern of native speciesMyriophyllum spicatumand invasive alien speciesElodea nuttalliiafter introduction of the latter one into the Drava River (Slovenia)

Mazej Grudnik, Zdenka, Germ, Mateja

Journal:

Year:

2013

Language:

english

File:

PDF, 427 KB

english, 2013

8

Characterization and commissioning of the SST-1M camera for the Cherenkov Telescope Array

Aguilar, J.A., Bilnik, W., Błocki, J., Bogacz, L., Borkowski, J., Bulik, T., Cadoux, F., Christov, A., Curyło, M., della Volpe, D., Dyrda, M., Favre, Y., Frankowski, A., Grudnik, Ł., Grudzińska, M., H

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2016

Language:

english

File:

PDF, 1.42 MB

english, 2016

9

Bioactive macrocyclic inhibitors of the PD-1/PD-L1 immune checkpoint

Magiera-Mularz, Katarzyna, Skalniak, Lukasz, Zak, Krzysztof M., Musielak, Bogdan, Rudzinska-Szostak, Ewa, Berlicki, Łukasz, Kocik, Justyna, Grudnik, Przemyslaw, Sala, Dominik, Zizigas-Zarganis, Tryfon

Journal:

Angewandte Chemie

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

10

[PP.19.13] POST OCCLUSIVE REACTIVE HYPEREMIC RESPONSE OF SKIN MICROCIRCULATION IN EXTREMELY OBESE HYPERTENSIVE AND NON-HYPERTENSIVE PATIENTS AFTER BARIATRIC SURGERY

Gryglewska, B., Gluszewska, A., Zarzycki, B., Dzieza-Grudnik, A., Fedyk-Lukasik, M., Major, P., Budzynski, A., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2017

Language:

english

File:

PDF, 82 KB

english, 2017

11

Reduction of 24-h blood pressure variability in extreme obese patients 10 days and 6 months after bariatric surgery depending on pre-existing hypertension

Głuszewska, Anna, Gryglewska, Barbara, Gąsowski, Jerzy, Bilo, Grzegorz, Zarzycki, Bartosz, Dzieża-Grudnik, Anna, Major, Piotr, Budzyński, Andrzej, Faini, Andrea, Parati, Gianfranco, Grodzicki, Tomasz

Journal:

European Journal of Internal Medicine

Year:

2018

Language:

english

File:

PDF, 263 KB

english, 2018

12

Development of a novel, high-affinity ssDNA trypsin inhibitor

Malicki, Stanislaw, Ksiazek, Miroslaw, Majewski, Pawel, Pecak, Aleksandra, Mydel, Piotr, Grudnik, Przemyslaw, Dubin, Grzegorz

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.12 MB

english, 2019

13

Structural analysis of PIM1 kinase complexes with ATP-competitive inhibitors

Bogusz, Jozefina, Zrubek, Karol, Rembacz, Krzysztof P., Grudnik, Przemyslaw, Golik, Przemyslaw, Romanowska, Malgorzata, Wladyka, Benedykt, Dubin, Grzegorz

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.55 MB

english, 2017

14

Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells

Skalniak, Lukasz, Zak, Krzysztof M., Guzik, Katarzyna, Magiera, Katarzyna, Musielak, Bogdan, Pachota, Magdalena, Szelazek, Bozena, Kocik, Justyna, Grudnik, Przemyslaw, Tomala, Marcin, Krzanik, Sylwia,

Journal:

Year:

2017

Language:

english

File:

PDF, 6.48 MB

english, 2017

15

Atomic resolution crystal structure of HV-BBI protease inhibitor from amphibian skin in complex with bovine trypsin

Grudnik, Przemyslaw, Debowski, Dawid, Legowska, Anna, Malicki, Stanislaw, Golik, Przemyslaw, Karna, Natalia, Rolka, Krzysztof, Dubin, Grzegorz

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2015

Language:

english

File:

PDF, 380 KB

english, 2015

16

PP.13.17

Dzieza-Grudnik, A., Sulicka-Grodzicka, J., Strach, M., Siga, O., Klimek, E., Korkosz, M., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2015

Language:

english

File:

PDF, 209 KB

english, 2015

17

Very early clinical vascular and heart markers of newly recognized hypertension in middle age adults

Siga, Olga, Królczyk, Jarosław, Dzieża-Grudnik, Anna, Walczewska, Jolanta, Wizner, Barbara, Grodzicki, Tomasz

Journal:

Artery Research

Year:

2015

Language:

english

File:

PDF, 39 KB

english, 2015

18

[PP.33.09] THE RELATIONSHIP BETWEEN RIGHT AND LEFT VENTRICLES IN PATIENTS WITH HYPERTENSION AND HEALTHY CONTROLS

Krolczyk, J., Siga, O., Dzieza-Grudnik, A., Walczewska, J., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2016

Language:

english

File:

PDF, 171 KB

english, 2016

19

Structural Characterization of Glycerol Kinase from the Thermophilic Fungus Chaetomium thermophilum

Wilk, Piotr, KuÅka, Katarzyna, WÄtor, ElÅ¼bieta, MaÅecki, Piotr H., WoÅ, Klaudia, Tokarz, Piotr, Dubin, Grzegorz, Grudnik, PrzemysÅaw

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 5.52 MB

2020

20

PP.33.21

Gluszewska, A., Gryglewska, B., Zarzycki, B., Dzieza-Grudnik, A., Fedyk-Lukasik, M., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2015

Language:

english

File:

PDF, 156 KB

english, 2015

21

PP.23.23

Walczewska, J., Siga, O., Dzieza-Grudnik, A., Wolkow, P., Borys, A., Krolczyk, J., Wizner, B., Gryglewska, B., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2015

Language:

english

File:

PDF, 67 KB

english, 2015

22

Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome – insights into the enzyme activation mechanism

Witkowska, Julia, Giżyńska, Małgorzata, Grudnik, Przemysław, Golik, Przemysław, Karpowicz, Przemysław, Giełdoń, Artur, Dubin, Grzegorz, Jankowska, Elżbieta

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.89 MB

english, 2017

23

ADHD and Conduct Disorder: An MRI Study in a Community Sample

Bussing, Regina, Grudnik, Jennifer, Mason, Dana, Wasiak, Marta, Leonard, Christiana

Journal:

The World Journal of Biological Psychiatry

Year:

2002

Language:

english

File:

PDF, 695 KB

english, 2002

24

Bioactive macrocyclic inhibitors of the PD-1/PD-L1 immune checkpoint

Magiera-Mularz, Katarzyna, Skalniak, Lukasz, Zak, Krzysztof M., Musielak, Bogdan, Rudzinska-Szostak, Ewa, Berlicki, Łukasz, Kocik, Justyna, Grudnik, Przemyslaw, Sala, Dominik, Zizigas-Zarganis, Tryfon

Journal:

Angewandte Chemie International Edition

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

25

[PP.12.04] EARLY EFFECTS OF BARIATRIC SURGERY ON SKIN MICROCIRCULATION IN EXTREMELY OBESE PATIENTS

Gluszewska, A., Gryglewska, B., Zarzycki, B., Dzieza-Grudnik, A., Fedyk-Lukasik, M., Matlok, M., Budzynski, A., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2016

Language:

english

File:

PDF, 103 KB

english, 2016

26

Arterial stiffness is not increased in patients with short duration rheumatoid arthritis and ankylosing spondylitis

Dzieża-Grudnik, Anna, Sulicka, Joanna, Strach, Magdalena, Siga, Olga, Klimek, Ewa, Korkosz, Mariusz, Grodzicki, Tomasz

Journal:

Year:

2016

Language:

english

File:

PDF, 907 KB

english, 2016

27

Crystal Structure of Mannose Specific IIA Subunit of Phosphotransferase System from Streptococcus pneumoniae

Magoch, Malgorzata, Nogly, Przemyslaw, Grudnik, Przemyslaw, Ma, Pikyee, Boczkus, Bozena, Neves, Ana Rute, Archer, Margarida, Dubin, Grzegorz

Journal:

Year:

2020

File:

PDF, 2.88 MB

2020

28

Insights into eukaryotic Rubisco assembly — Crystal structures of RbcX chaperones from Arabidopsis thaliana

Kolesinski, Piotr, Golik, Przemyslaw, Grudnik, Przemyslaw, Piechota, Janusz, Markiewicz, Michał, Tarnawski, Miroslaw, Dubin, Grzegorz, Szczepaniak, Andrzej

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

29

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)

Zak, Krzysztof M., Grudnik, Przemyslaw, Guzik, Katarzyna, Zieba, Bartosz J., Musielak, Bogdan, Dömling, Alexander, Dubin, Grzegorz, Holak, Tad A.

Journal:

Year:

2016

Language:

english

File:

PDF, 3.72 MB

english, 2016

30

Influence of resin content on the surface covered with adhesive

Medved, Sergej, Grudnik, Jure

Journal:

International Journal of Adhesion and Adhesives

Year:

2020

File:

PDF, 1.55 MB

2020

31

A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction

Surmiak, Ewa, Twarda-Clapa, Aleksandra, Zak, Krzysztof M., Musielak, Bogdan, Tomala, Marcin D., Kubica, Katarzyna, Grudnik, Przemysław, Madej, Mariusz, Jabłoński, Mateusz, Potempa, Jan, Kalinowska-Tłu

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 1.33 MB

english, 2016

32

[PP.23.05] CENTRAL BLOOD PRESSURE AND ARTERIAL WAVE REFLECTION IN RESISTANT HYPERTENSION

Siga, O., Dzieza-Grudnik, A., Walczewska, J., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2016

File:

PDF, 110 KB

2016

33

Chromosomal localization of PemIK toxin-antitoxin system results in the loss of toxicity â Characterization of pemIK-Sp from Staphylococcus pseudintermedius

Janczak, Monika, Hyz, Karolina, Bukowski, Michal, Lyzen, Robert, Hydzik, Marcin, Wegrzyn, Grzegorz, Szalewska-Palasz, Agnieszka, Grudnik, Przemyslaw, Dubin, Grzegorz, Wladyka, Benedykt

Journal:

Microbiological Research

Year:

2020

File:

PDF, 1.60 MB

2020

34

T cell Activation Is Driven by an ADP-Dependent Glucokinase Linking Enhanced Glycolysis with Mitochondrial Reactive Oxygen Species Generation

Marcin M. Kamiński, Sven W. Sauer, Marian Kamiński, Silvana Opp, Thorsten Ruppert, Paulius Grigaravičius, Przemysław Grudnik, Hermann-Josef Gröne, Peter H. Krammer, Karsten Gülow

Journal:

Year:

2012

Language:

english

File:

PDF, 2.78 MB

english, 2012

35

Structural basis for the molecular evolution of SRP-GTPase activation by protein

Bange, Gert, Kümmerer, Nico, Grudnik, Przemyslaw, Lindner, Robert, Petzold, Georg, Kressler, Dieter, Hurt, Ed, Wild, Klemens, Sinning, Irmgard

Journal:

Nature Structural and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 797 KB

english, 2011

36

Investigation of Serine-Proteinase-Catalyzed Peptide Splicing in Analogues of Sunflower Trypsin Inhibitor 1 (SFTI-1)

Karna, Natalia, Łęgowska, Anna, Malicki, Stanisław, Dębowski, Dawid, Golik, Przemysław, Gitlin, Agata, Grudnik, Przemysław, Wladyka, Benedykt, Brzozowski, Krzysztof, Dubin, Grzegorz, Rolka, Krzysztof

Journal:

Year:

2015

Language:

english

File:

PDF, 2.60 MB

english, 2015

37

Small-molecule inhibitors of the Programmed Cell Death-1/Programmed Death-ligand 1 (PD-1/PD-L1) interaction via transiently-induced protein states and dimerization of PD-L1

Guzik, Katarzyna, Zak, Krzysztof M., Grudnik, Przemyslaw, Magiera, Katarzyna, Musielak, Bogdan, Törner, Ricarda, Skalniak, Lukasz, Dömling, Alexander, Dubin, Grzegorz, Holak, Tad A

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.08 MB

english, 2017

38

Structural basis for ADP-dependent glucokinase inhibition by 8-bromo-substituted adenosine nucleotide

Grudnik, Przemyslaw, Kaminski, Marcin M, Rembacz, Krzysztof P, Kuska, Katarzyna, Madej, Mariusz, Potempa, Jan, Dawidowski, Maciej, Dubin, Grzegorz

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 1.84 MB

english, 2018

39

PP.26.01

Siga, O., Dzieza-Grudnik, A., Walczewska, J., Krolczyk, J., Wizner, B., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2015

Language:

english

File:

PDF, 131 KB

english, 2015

40

Influence of abiotic factors on invasive behaviour of alien species Elodea nuttallii in the Drava River (Slovenia)

Grudnik, Zdenka Mazej, Jelenko, Ida, Germ, Mateja

Journal:

Annales de Limnologie - International Journal of Limnology

Year:

2014

Language:

english

File:

PDF, 840 KB

english, 2014

41

Half Way to HypusineâStructural Basis for Substrate Recognition by Human Deoxyhypusine Synthase

WÄtor, ElÅ¼bieta, Wilk, Piotr, Grudnik, PrzemysÅaw

Journal:

Year:

2020

File:

PDF, 3.30 MB

2020

42

Structural Basis of GD2 Ganglioside and Mimetic Peptide Recognition by 14G2a Antibody

Horwacik, Irena, Golik, Przemyslaw, Grudnik, Przemyslaw, Kolinski, Michal, Zdzalik, Michal, Rokita, Hanna, Dubin, Grzegorz

Journal:

Molecular & Cellular Proteomics

Year:

2015

Language:

english

File:

PDF, 3.19 MB

english, 2015

43

[PP.23.14] CONTROL OF BLOOD PRESSURE AND DIASTOLIC FUNCTION OF LEFT AND RIGHT VENTRICLE IN HYPERTENSIVE PATIENTS

Dzieza-Grudnik, A., Siga, O., Walczewska, J., Krolczyk, J., Rewiuk, K., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2016

Language:

english

File:

PDF, 176 KB

english, 2016

44

PP.LB03.23

Gluszewska, A., Bilo, G., Faini, A., Zarzycki, B., Gryglewska, B., Dzieza-Grudnik, A., Fedyk-Lukasik, M., Grodzicki, T., Parati, G.

Journal:

Journal of Hypertension

Year:

2015

Language:

english

File:

PDF, 333 KB

english, 2015

45

[PP.05.28] RELATIONSHIP BETWEEN UROCORTIN 2 CONCENTRATION AND METABOLIC PROFILE IN HEALTHY SUBJECTS

Siga, O., Dzieza-Grudnik, A., Walczewska, J., Wolkow, P., Borys, A., Wizner, B., Gryglewska, B., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2017

Language:

english

File:

PDF, 117 KB

english, 2017

46

Macrocyclic Peptide Inhibitor of PDâ1/PDâL1 Immune Checkpoint

MagieraâMularz, Katarzyna, Kuska, Katarzyna, Skalniak, Lukasz, Grudnik, Przemyslaw, Musielak, Bogdan, Plewka, Jacek, Kocik, Justyna, Stec, Malgorzata, Weglarczyk, Kazimierz, Sala, Dominik, Wladyka,

Journal:

Advanced Therapeutics

Year:

2020

File:

PDF, 2.57 MB

2020

47

[OP.7A.09] UROCORTIN2 LEVELS IN PATIENTS WITH RESISTANT HYPERTENSION TREATED WITH ACEI OR ARB

Walczewska, J., Siga, O., Dzieza-Grudnik, A., Wolkow, P., Borys, A., Krolczyk, J., Wizner, B., Gryglewska, B., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2017

Language:

english

File:

PDF, 106 KB

english, 2017

48

EFFECTS OF BARIATRIC SURGERY ON ENDOTHELIAL FUNCTION IN EXTREMELY OBESE PATIENTS

Rewiuk, K., Gluszewska, A., Gryglewska, B., Gasowski, J., Zarzycki, B., Dzieza-Grudnik, A., Major, P., Budzynski, A., Grodzicki, T.

Journal:

Journal of Hypertension

Year:

2018

Language:

english

File:

PDF, 121 KB

english, 2018

49

Heavy metals and arsenic concentrations in ten fish species from the

Samar Al Sayegh Petkovšek, Zdenka Mazej Grudnik, Boštjan Pokorny

Journal:

Environmental Monitoring and Assessment

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

50

Effects of bariatric surgery on endothelial function in extremely obese patients

Dzieża-Grudnik, Anna, Głuszewska, Anna, Rewiuk, Krzysztof, Kwater, Aleksander, Zarzycki, Bartosz, Fedyk-Łukasik, Małgorzata, Gryglewska, Barbara, Grodzicki, Tomasz

Journal:

Artery Research

Year:

2015

Language:

english

File:

PDF, 43 KB

english, 2015

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